Information on the importance of the longitudinal pre-processing stream, and steps on how to run it are listed here and here. In summary, the longitudinal stream extracts reliable volume and thickness estimations across individuals over time by using an unbiased within-subject template space and image. There are 3 main steps:
1. Recon-all
Cross sectionally process all time points with the default recon-all pipeline (manually or automatically)
| Code Block |
|---|
recon-all -i FTD####.nii -subjid subject1_tp1 -all |
2. Base
Create an unbiased template from all time points for each subject.
| Code Block |
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recon-all -base subject1_template -tp subject1_tp1 -tp subject1_tp2 -tp subject1_tp3 ... -all |
3. Long
Longitudinally process all time points
| Code Block |
|---|
recon-all -long subject1_tp1 subject1_template -all
recon-all -long subject1_tp2 subject1_template -all
recon-all -long subject1_tp3 subject1_template -all |